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שיכור פונקציה להקצות polo like kinase 1 מרהיב בית חולים דובדבן

Structure-Guided Design and Development of Potent and Selective Dual  Bromodomain 4 (BRD4)/Polo-like Kinase 1 (PLK1) Inhibitors | Journal of  Medicinal Chemistry
Structure-Guided Design and Development of Potent and Selective Dual Bromodomain 4 (BRD4)/Polo-like Kinase 1 (PLK1) Inhibitors | Journal of Medicinal Chemistry

Molecular and structural basis of polo-like kinase 1 substrate recognition:  Implications in centrosomal localization | PNAS
Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization | PNAS

Peptidomimetics Targeting the Polo-box Domain of Polo-like Kinase 1 |  Journal of Emerging Investigators
Peptidomimetics Targeting the Polo-box Domain of Polo-like Kinase 1 | Journal of Emerging Investigators

Polo-like Kinase 1 Facilitates Chromosome Alignment during Prometaphase  through BubR1* - Journal of Biological Chemistry
Polo-like Kinase 1 Facilitates Chromosome Alignment during Prometaphase through BubR1* - Journal of Biological Chemistry

Development of a Polo-like Kinase-1 Polo-Box Domain Inhibitor as a Tumor  Growth Suppressor in Mice Models | Journal of Medicinal Chemistry
Development of a Polo-like Kinase-1 Polo-Box Domain Inhibitor as a Tumor Growth Suppressor in Mice Models | Journal of Medicinal Chemistry

Functional Dynamics of Polo-Like Kinase 1 at the Centrosome | Molecular and  Cellular Biology
Functional Dynamics of Polo-Like Kinase 1 at the Centrosome | Molecular and Cellular Biology

Cancers | Free Full-Text | The Emerging Role of Polo-Like Kinase 1 in  Epithelial-Mesenchymal Transition and Tumor Metastasis | HTML
Cancers | Free Full-Text | The Emerging Role of Polo-Like Kinase 1 in Epithelial-Mesenchymal Transition and Tumor Metastasis | HTML

Pharmaceuticals | Free Full-Text | Inhibition of Polo-like Kinase 1 by  HMN-214 Blocks Cell Cycle Progression and Inhibits Neuroblastoma Growth
Pharmaceuticals | Free Full-Text | Inhibition of Polo-like Kinase 1 by HMN-214 Blocks Cell Cycle Progression and Inhibits Neuroblastoma Growth

Polo-like kinases: structural variations lead to multiple functions |  Nature Reviews Molecular Cell Biology
Polo-like kinases: structural variations lead to multiple functions | Nature Reviews Molecular Cell Biology

Polo-like kinase 1 (PLK1) signaling in cancer and beyond - ScienceDirect
Polo-like kinase 1 (PLK1) signaling in cancer and beyond - ScienceDirect

Genes | Free Full-Text | The Mitotic Cancer Target Polo-Like Kinase 1:  Oncogene or Tumor Suppressor? | HTML
Genes | Free Full-Text | The Mitotic Cancer Target Polo-Like Kinase 1: Oncogene or Tumor Suppressor? | HTML

Figure 2 from Polo-like kinase (PLK) inhibitors in preclinical and early  clinical development in oncology. | Semantic Scholar
Figure 2 from Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncology. | Semantic Scholar

Development of ultra-high affinity bivalent ligands targeting the polo-like  kinase 1 - RSC Chemical Biology (RSC Publishing)
Development of ultra-high affinity bivalent ligands targeting the polo-like kinase 1 - RSC Chemical Biology (RSC Publishing)

Polo-Like Kinase 1 (PLK-1) - IHC Primary Antibodies
Polo-Like Kinase 1 (PLK-1) - IHC Primary Antibodies

Polo-like Kinase 1 Licenses CENP-A Deposition at Centromeres - ScienceDirect
Polo-like Kinase 1 Licenses CENP-A Deposition at Centromeres - ScienceDirect

Development of Bifunctional Inhibitors of Polo‐Like Kinase 1 with  Low‐Nanomolar Activities Against the Polo‐Box Domain - Scharow - 2016 -  ChemBioChem - Wiley Online Library
Development of Bifunctional Inhibitors of Polo‐Like Kinase 1 with Low‐Nanomolar Activities Against the Polo‐Box Domain - Scharow - 2016 - ChemBioChem - Wiley Online Library

Mammalian Polo-like Kinase 1 (Plk1) Promotes Proper Chromosome Segregation  by Phosphorylating and Delocalizing the PBIP1·CENP-Q Complex from  Kinetochores - Journal of Biological Chemistry
Mammalian Polo-like Kinase 1 (Plk1) Promotes Proper Chromosome Segregation by Phosphorylating and Delocalizing the PBIP1·CENP-Q Complex from Kinetochores - Journal of Biological Chemistry

Switching Polo-like kinase-1 on and off in time and space: Trends in  Biochemical Sciences
Switching Polo-like kinase-1 on and off in time and space: Trends in Biochemical Sciences

Polo-Like Kinase 1 Directs Assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF  Complex to Initiate Cleavage Furrow Formation | PLOS Biology
Polo-Like Kinase 1 Directs Assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF Complex to Initiate Cleavage Furrow Formation | PLOS Biology

Polo-like kinase 1 (PLK1) signaling in cancer and beyond - ScienceDirect
Polo-like kinase 1 (PLK1) signaling in cancer and beyond - ScienceDirect

Regulation of mitotic progression by Polo-like kinase 1 (PLK1). PLK1... |  Download Scientific Diagram
Regulation of mitotic progression by Polo-like kinase 1 (PLK1). PLK1... | Download Scientific Diagram

Frontiers | A Perspective on Polo-Like Kinase-1 Inhibition for the  Treatment of Rhabdomyosarcomas
Frontiers | A Perspective on Polo-Like Kinase-1 Inhibition for the Treatment of Rhabdomyosarcomas

Functions of Polo-Like Kinases: A Journey From Yeast To Humans | Bentham  Science
Functions of Polo-Like Kinases: A Journey From Yeast To Humans | Bentham Science

Discovery and development of the Polo-like kinase inhibitor volasertib in  cancer therapy | Leukemia
Discovery and development of the Polo-like kinase inhibitor volasertib in cancer therapy | Leukemia

Polo Like Kinase-enzyme
Polo Like Kinase-enzyme